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Re: Selegiline Info??-Scott

Posted by Scott L. Schofield on November 10, 1999, at 14:14:46

In reply to Re: Selegiline Info??-Scott, posted by Adam on November 9, 1999, at 18:01:27

> I typically do Advanced PubMed Searches and use search words
like "selegiline", "L-deprenyl", "(-)-deprenyl" "Eldepryl" ,
"depression" , "antidepressant" and so on and came up with very
little that seemed relevant. I might wind up on tranylcypromine. This has me a bit scared.
The best thing about selegiline (taken transdermally, at least)
has been its tolerability. If I don't react well to
tranylcypromine? Such is the path I've chosen. What I guess was hypomania went away after a couple weeks, I
felt a bit down (I rather liked the hypomanic me). <

Oh yeah - keep an eye out for the precipitation of mania. If you
did indeed experience hypomania with selegiline, a "full-blown"
mania might occur with *any* drug. If you do get manic, you
probably won't recognize it as such. You might not even believe
the people around you when they tell you that you are manic. I
didn't. I thought it was a good idea for me to let my family know
to be on the alert. Chances are, you don't have this potential at
all. (I don't mean to scare you any more than you are already.
It's just a reasonable caveat).

I think MAO-inhibitors are making a come-back. It was criminal for
psychiatrists to avoid prescribing them. I couldn't believe it
when I read posts in which even tricyclics were avoided. I should
think that after trying five different SSRIs in succession without
results, one might at least entertain the idea of using one of
them. Imipramine (Tofranil) IS the "gold-standard" by which other
antidepressants are compared.

* Requisite disclaimer.




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