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Re: ? for Saint J: dexe vs Adderall <<-SAY WHAT?

Posted by saint james on October 29, 1999, at 3:22:55

In reply to Re: ? for Saint J: dexe vs Adderall <<-SAY WHAT?, posted by cityboy on October 27, 1999, at 1:14:17

> Obetrol was not pulled because of "abuse" exclusively. It was discontinued because the AMA re-evaluated the use of amphetamine for long
> term obesity therapy. At the same time, the AMA discontinued the use of all amphetamine/barbiturate mixtures, calling them
> irrational; e.g., Obedrine, Eskatrol, Biphetamine-T, all of which were called "goof balls."

Obetrol was a single agent ( really 4, but all amphetamines) no barbiturate

> Pardon me, but you have these terms mixed up.
> The "D" refers to "dextro" or RIGHT HAND ROTATION of the molecules.

This is what happens when you have mixed domance.
Thanks for the correction !

> Another difference between the two is the way the almighty DEA "sees" them.
> Dexedrine is classified as a CONTROL II substance, whereas benzedrine, as
> a rule, is considered a CONTROL III drug (DIDREX, an anoretic from UpJohn).

Didrex is not and amphetamine. All amphetamines are Sch II

> I suppose you could mix the two, but that would send the DEA into a tizzy.
> ADDERALL, from what I understand, contains amphetamine resins, whatever that crap is.

Adderal is 4 chems, d-amphetamine as 2 salts and l-amphetamine as 2 salts. resin(s) refers to the slow release agent the amphetamines are bound in, thus making a slow release med.

> > Dex is all d-amphetamine, proven to be active in humans.
> > L-amphetamine has some action, but tends to have more negative effects. Reported are: makes you more shakey, dysphoria, sweaty, ect.
> ^^^^^^^^^
> See DIDREX reference above.
> > The D vers is more smooth feeling.
> ^^^^^^^^^^^^^^
> Meaning what?

Causes less negative effects, like sweating. Tends to cause disphoria

> > "Least patentable difference" is the least chemical difference you can change a compound from the patent to get another patent. In this case it is the addition of L-amphetamine, and a few other things.
> ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
> This makes no sense at all, sorry.

EX... take Prozac (a patent) and change one atom,
then you can patent it as a new drug, which may or may not be the same as Prozac in effect. This was done with the TCA's...Tofrinil was the first
AD, someone got a patent on it. A slight change of atoms produced all the other TCA's and each new AD had enough difference so the make could get a new patent. This is "least pattentable difference"





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