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Re: Dopamine & Effexor -- At What Dose???

Posted by anita on July 9, 1999, at 23:41:36

In reply to Re: Dopamine & Effexor -- At What Dose???, posted by saintjames on July 9, 1999, at 4:01:51

> > Hi,
> >
> > I remember reading somewhere that dopamine reuptake inhibition
> > occurs with Effexor only at high doses. But I can't remember at
> > what dose (225mg? 325mg?) and I can't find the reference anymore.
> >
> > If you know, please reply, it's very important.
> >
> > thanks,
> > anita
> James here....
> It has weak dopamine reuptake inhibition ( compaired to 5HT and nor-e) but I notice a difference (for me and me only !) at 100 mgs that is different than any AD, and I associate this with Dopamine. It is a non mood cognation improving effect that really helps with the ADD. I've looked for the same info and have not found it but assume it takes a higher dose to get sig. effect. I take 200-300.
> What is your intrest in Dopamine ?
> Beware....St James can take large doses of all meds with little side effect. You need to talk with your doc b4 upping any dose, but esp. Effexor
> because many have nasty side effects with greater doses. Too much of a good thing is not always good !
> j

Hi James,

Thanks for the input. I could swear someone on Psycho-Babble mentioned a specific
dose once, but alas I cannot find it.I wish Dr. Bob had a search feature for the
Psycho-Babble posts, but that's another topic...

I'm interested in dopamine because the only meds that have had a good effect for
me have had some dopaminergic action (Nardil, Parnate, ritalin, prozac), and for various
reasons I cannot take them. So, for me, I'm pretty convinced dopamine = less depression.
I'm currently taking 225mg Effexor, but I despair of going much higher due to side effects,
and I'm tempted to just give up on it and try Marplan, tho I fear weight gain and excessive

Well, you asked :-)





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