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Re: Parnate - Elizabeth

Posted by Elizabeth on June 14, 1999, at 1:36:19

In reply to Re: Parnate - Elizabeth, posted by Judy on June 6, 1999, at 10:58:40

Hi Judy. I'm sorry I missed this post. I haven't been spending much time online lately (well, compared to how much time I usually spend online).

>I can't tell you how much I envy the fact that your "Big O" Seratonin receptor hasn't been switched off by Nardil! You should really consider yourself fortunate in that respect!

I never had any problems with antidepressants and (insert euphemism here). It is something that I'm grateful for.

> Since this isn't one of your side effects, I guess I can't ask you if there is any way to counteract this - ginkgo or something. Maybe someone else out there has experienced this phenomenon and has a suggestion.

Even though Wellbutrin made you anxious before, maybe that would work. I know it's helped a lot of people who were having this problem with SSRIs.

> As for Parnate, could you explain what you mean by spontaneous hypertention? I've been very susceptible to the 'jitters' caused by some other AD's (Wellbutrin almost did me in!) and I don't like the sound of this. Also, does Parnate cause the same lowered blood pressure 'woosies' as Nardil when you stand up too quickly?

Spontaneous as opposed to being triggered by a food-drug or drug-drug interaction. Like, I didn't eat any of the wrong things, but I got high blood pressure (high enough to merit taking a Procardia) anyway.

Parnate does cause orthostatic hypotension (low BP when you stand up) for some people. I found it worse with Nardil (even though I've been taking a beta blocker with the Parnate).

> What have you heard about Marplan - do you think it might provide a "happy medium" between Nardil and Parnate?

Well, that it isn't so prone to cause weight gain as Nardil. But because it's a hydrazine derivative (same subfamily as Nardil but not Parnate), it should (like Nardil) be GABAergic and have good effects on anxiety (for which Parnate has been kind of disappointing). In other words, that it may have the best of both worlds.




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