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Re: Amantadine For Depression?

Posted by Chris A. on June 10, 1999, at 1:38:09

In reply to Amantadine For Depression?, posted by JohnB on June 9, 1999, at 22:47:47

Amantadine may be promising for bipolar and major depression. One bug hurdlie in its use is that it is lethal in relatively small overdoses. No pDoc in their right mind would send a depressed patient home with an Rx for it if they even so much as glanced at the PDR entry. I took a few doses when the rest of my family had influenza A and retrospectively noticed an improvement in my mood (I didn't get the flu, either).

I've been on a combination of 2 AD's for over a year with ok results. My doctor recently added methylphenidate which really reached the deepest pits of depression. The problem, though, is that it only lasts about an hour at a time, then falls off, then peaks, etc. This has been very frustrating. The sustained release version was no better. I'd like to try a longer lasting, smoother acting dopamine enhancing med that might end the peaks and valleys. I've heard spme amazing things about amantadine, an anti-viral that enhances dopamine consistently. Has anyone tried amantadine out there? Any other suggestions?
Keep watching the research and working with your meds until you find the right cocktail.


Chris A.




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