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Re: Marplan benefits?

Posted by JD on May 29, 1999, at 11:54:32

In reply to Re: Marplan benefits?, posted by Elizabeth on May 27, 1999, at 22:42:12

Hi Annie,

As someone who's been getting closer and closer to trying an MAOI myself, I've too have done my share of looking into Marplan lately. As Elizabeth says, my sense is also that it can kind of be placed "between" Parnate and Nardil in the scheme of things--generally not as much weight gain as with Nardil, not as activating and pro-hypertensive as Parnate. Sounds ideal, no? The question is whether it's as effective, since Parnate and Nardil have more research behind them and have very solid reputations despite their unpleasant side effects. Though it's clearly a very potent med, not very much is known about how Marplan compares in studies with other drugs, even with other MAOIs--as I've mentioned elsewhere, some doctors anecdotally claim it's not as good, but some patients apparently swear by it. Interestingly, part of the recent FDA re-approval in the US even included uncertainty over what the proper dosages were. My guess is that it's at least worth a try for many people in the MAOI market, especially for people who have problems with Nardil and Parnate...





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