Psycho-Babble Medication | about biological treatments | Framed
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Re: Reboxetine/refractory BD-1 depression

Posted by Nancy on April 21, 1999, at 9:58:00

In reply to Re: Reboxetine (Edronax) , posted by Jeff on April 15, 1999, at 3:15:04

> > I'd also like to know about Reboxetine in hard-to-treat, refractory depression, and how someone in the US can get a scrip. (Hey, flights to England are cheap these days, anyone know a doc interested in a *really* challenging case..?)
> >
> > Thanks,
> > -dina.
> >
> I was eager to try Reboxetine and ordered it online from a Swiss pharmacy in Zurich, Victoria Apotheke ( I am a
> very treatment-resistant BP2. I found the Reboxetine showed signs of working within 24-hours - but I am a quick responder. But it had positive
> effect after several days. I don't recall any major side-effects. I felt activated and motivated and had much more energy. I still had negative
> feelings and thoughts, so we added Prozac in conjunction after two weeks. The Prozac caused an
> immediate reversal of all the postive effects - within 24 hours. Prozac was stopped and - within 12 hours - the postive effects of the Reboxetine returned. After 5 weeks, the effects of the Reboxetine 'faded" away and could not be restarted
> even with increases in dosage. (This is my normal
> pattern with medications and may not apply to others.)

I'm severe bipolar-1, ultra-rapid cycling, anguished mixed states, treatment resistive, and chronically suicidal. No medication would work with my physiology until a brilliant pdoc insisted that my T3 and T4 thyroid levels MUST BOTH BE IN THE UPPER QUARTILE OF THE NORMAL RANGE. Once this was achieved, medication did what it was supposed to do. I was fortunate that the first AD (300mg Effexor XR) worked. Before upper quartile thyroid augmentation, I was treatment resistive in every trial on every US available AD (including 300mg Effexor XR).

I'm wondering if others with similar experience will compare their preferences for either Edronax or Effexor.




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