Psycho-Babble Medication | about biological treatments | Framed
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Re: Tianeptine anybody?

Posted by Andrew on April 19, 1999, at 17:55:49

In reply to Tianeptine anybody?, posted by George O. on April 6, 1999, at 20:26:58

> I've ordered this novel tricyclic from overseas, it may be may last chance. I've read lots about it on medline but haven't heard from anyone who's actually been on it. Tricyclics were about the only thing that ever helped me, problem is that after a couple of years I get immune to them. I've been on EVERYTHING and not much has helped the last few years, some thihgs that seemed promising, like reboxetine, actually made me much more depressed, it just doesn't make sense. Since this med is so novel (it inhances seretonin reuptake) it may work where others have failed, who knows? George.

I've ordered Tianeptine from overseas also. I hope this medicine provides you some benefits but I also think you shouldn't consider this your 'last chance' since everything is the last chance until something else is found to try.
I started taking Tianeptine at a low dose 2 days ago and plan to work up to the reccomended dose slowly barring unpleasent (side)effects.
I'm confused on just how Tianeptine works. It increases seretonin reuptake, but does it only increase reuptake at specific seretonin receptor sites? I read somewhere that its real effectiveness actually lay in its ability to reduce cortisol levels. This is interesting since Pivagabine is a coritsol reducer and in early trials has been effective in treating dysthymia.
I also thought it was very interesting that Tianeptine is described as both an antidepressent and a stimulant and is effective for combinations of depression and anxiety. That would be great to feel more energetic yet less anxious.




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