Posted by Seamus on March 14, 1999, at 9:47:15
In reply to Parnate & spontaneous hypertension, posted by Annie on March 6, 1999, at 15:51:41
> I've read several things here and elsewhere on Dr Bob's site about Parnate sometimes causing spontaneous hypertension. In January I started Parnate. The day prior my BP was 127/78. After three days on Parnate, my BP was 199/110. I was adhering to the strictest diet so I know it was not a tyramine reaction. I stopped Parnate. Here's the problem. My BP did not return to normal. The following week, my internist put me on Dyazide and then added Norvasc. It has dropped to 160/90. Did the BP of other people who experienced spontaneous hypertension from Parnate remain elevated? Is there a chance my BP could still return to normal or am I now stuck taking this nauseating med for life?
Have you been tested for pheochromocytoma?
Its a tumor of certain cells (usually in the adrenal glands) which causes them to excrete too much adrenaline.
This adrenaline, combined w/ the Parnate, could cause the hypertension you speak of.
A couple labs tests, HVA and VMA, after a washout period on the Parnate, should be able to answer the question.