Psycho-Babble Medication | about biological treatments | Framed
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Re: Paxil then Zoloft now Paxil

Posted by Matt on March 12, 1999, at 23:02:32

In reply to Paxil then Zoloft now Paxil, posted by JennyAnn on March 8, 1999, at 20:16:42

> I initially took paxil for depression and found great relief. After 8 months, found a great well of anxiety depression had masked. I decided (with my Doc) to change to Zoloft to try to minimize anxiety. I feel crazy...after 21 days I am in a deep depression and really I am going to stabalize on paxil and then...? who there a window of therapeutic benefit for SSRI's? Is there a habituation effect wherein i would need to increase the dose after so many months? Has there been a reported negative response to zoloft? am I alone?
> JA

Did you try upping the dose of Paxil prior to switching to Zoloft? Have you considered adding a benzodiazepine like Klonopin? (IME it helped hugely with my anxiety.) It would help with the anxiety and sleeplessness.

Remeron is terrific with anxiety, and it's great with sleep. It can cause sedation initially and weight gain, though there is less weight gain at higher doses.

As has been mentioned, SSRIs can poop out. There's lots of hypotheses as to why this happens, but no one really is sure why it does. There are lots of things that one can use to augment an SSRI (e.g. a tricyclic, or BuSpar.)

Good luck with things. I hope you feel better soon.





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