Posted by Elizabeth on February 10, 1999, at 17:26:22
In reply to When the medicine stops working, posted by Julian Grow on February 6, 1999, at 16:48:19
Has your wife always been using the same antidepressant (Paxil, you say later), or has she used different ones every time?
Sometimes antidepressants can cause rebound depression when they stop working; it sounds like that is what your wife is experiencing. Naltrexone might be appropriate for this.
Good luck to both of you.