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Re: topirimate in Bipolar Disorder

Posted by Toby on January 4, 1999, at 15:04:13

In reply to topirimate in Bipolar Disorder, posted by Chris A. on January 2, 1999, at 4:20:12

Some good studies on Topirimate have been published this year, using it alone and as an add-on to other mood stabilizers that are incompletely effective. I haven't seen where it is effective for depression alone, but I have seen it stop mania dead in its tracks (both these patients were on it without another mood stabilizer). The researchers say that it causes cognitive dulling but in my patients, I've warned them ahead of time and all have reported back that it has not happened to them (a sample size of only 9 patients, though). Good luck.




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