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Re: Codeine for depression? Yup

Posted by Dr. Dan on August 28, 1998, at 1:35:52

In reply to Re: Codeine for depression? Yup, posted by Ictinus on July 19, 1998, at 5:43:16

> Wait a minute Doc...

> Chronic pain often results in depression and in that sense narcotics might be beneficial. Could that be what Delphine read/heard?

> I also wonder if the mild euphorogenic/anxiolotic effects of codeine might temporarily relieve symptoms of dysthymia/anxiety. Isn't that the self-medication theory of drug use/abuse?

> Respectfully, your response echos old thinking about amphetamines & depression. Stimulants can create but also (safely) relieve depression.

Dr., I'm afraid I have a bee to put in your bonnet re: codeine for depression?
I have read many studies of codeine and morphine and other opiate analogs used to treat depression with success. I refer you to Goodwin & Jamison "Manic Depressive Illness" for a very good summary of studies regarding the use of opiate analogues to treat depression. Remember, Codeine will depress the CNS which doesn't always translate into depressed mood. I only know of one patient currently being treated with codeine on a PRN basis along with maintenance treatmet with an SSRI.
Thanks for listening.




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