Psycho-Babble Medication | about biological treatments | Framed
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Enter MK-869; time to rethink this...

Posted by Ictinus on December 19, 1998, at 23:51:10

In reply to Codeine for depression?, posted by Delphine on June 12, 1998, at 18:28:05

In September researchers at Merck published results of preclinical studies of a novel drug (MK-869) that has robust antidepressant effects. Why is this important? The drug effects the same nerve pathways as codeine (and other opoids). Codeine mimics endorphins/enkephalins which in effect block the release or effect of a transmitter called substance P. MK-869 also antagonizes substance P. Indeed it was created as a pain/migraine med.

So it seems we need to be less closed minded to ideas such as antidepressant effects of Codeine.

To read more about MK-869 online, try this link:




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