Psycho-Babble Medication | about biological treatments | Framed
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TCA and MAOI Combo?? Help anyone?

Posted by Annie on November 11, 1998, at 22:23:46

I have treatment resistant depression and thought I had been on every conceivable combination with varying degrees of minor improvement. After being off meds for about 6 months so that I could take part in various trials, like rTMS and P Substance antagonists, I started to get suicidal ideations again and agreed with my doctor that I'd try the meds route again. I am currently taking 250mg of desipramine with little positive response and my doctor says the next step is to increase to 300mg and then augment with a MAO Inhibitor. I see mention of this combination on the web as being helpful in some cases, but it scares me that all the drug descriptions say the combination can be fatal. Has anyone else had success with this combo? I know it's ironic that someone who is suicidal would be afraid to die from prescribed medications, but maybe it's a control issue - LOL! In all honesty, I don't want to die, I just don't want to live like this. If this combo has a slim chance of helping me, I guess I'll take it.




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